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Genome Sequences

Genome Sequences of Two GH Clade SARS-CoV-2 Strains Isolated from Patients with COVID-19 in South Korea

Minwoo Kim, Youn-Jung Lee, Jae Sun Yoon, Jin Young Ahn, Jung Ho Kim, Jun Yong Choi, Jong-Won Oh
Simon Roux, Editor
Minwoo Kim
aDepartment of Biotechnology, Yonsei University, Seoul, South Korea
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Youn-Jung Lee
bDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
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Jae Sun Yoon
bDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
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Jin Young Ahn
bDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
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Jung Ho Kim
bDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
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Jun Yong Choi
bDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
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  • ORCID record for Jun Yong Choi
Jong-Won Oh
aDepartment of Biotechnology, Yonsei University, Seoul, South Korea
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Simon Roux
DOE Joint Genome Institute
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DOI: 10.1128/MRA.01384-20
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    FIG 1

    Phylogenetic tree of the genome sequences of SARS-CoV-2/human/KOR/YS006/2020 and SARS-CoV-2/human/KOR/YS008/2020, along with 58 other randomly chosen sequences, including 30 sequences of South Korean isolates of SARS-CoV-2 retrieved from Nextstrain (nextstrain.org). Multiple sequence alignments were conducted with MUSCLE v3.8.31 (12), and the phylogenetic tree was constructed using the Molecular Evolutionary Genetics Analysis (MEGA) v7.0 software by the neighbor-joining method with 1,000 bootstrap replicates (13). Shown in parentheses after the strain name and GISAID accession number are the clade to which it belongs and the collection date (month-day) for each strain. The sequences reported in this announcement are shown in bold. The SARS-CoV-2 isolates are presented in seven different colors for the different clades (shown in the key), classified according to GISAID classification. The scale bar represents the number of nucleotide substitutions per site.

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  • TABLE 1

    Nucleotide and amino acid changes in the YS006 and YS008 strains, in comparison to the reference strain

    TABLE 1
    • ↵a Reference strain Wuhan/Hu-1/2019 (nucleotides 1 to 29870).

    • ↵b ORF, open reading frame; nsp, nonstructural protein; E, envelope; N, nucleocapsid.

    • ↵c Amino acid changes present in the YS006 and YS008 strains, in comparison to the reference strain.

    • ↵d A nonsynonymous substitution present only in the YS008 strain.

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Genome Sequences of Two GH Clade SARS-CoV-2 Strains Isolated from Patients with COVID-19 in South Korea
Minwoo Kim, Youn-Jung Lee, Jae Sun Yoon, Jin Young Ahn, Jung Ho Kim, Jun Yong Choi, Jong-Won Oh
Microbiology Resource Announcements Jan 2021, 10 (1) e01384-20; DOI: 10.1128/MRA.01384-20

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Genome Sequences of Two GH Clade SARS-CoV-2 Strains Isolated from Patients with COVID-19 in South Korea
Minwoo Kim, Youn-Jung Lee, Jae Sun Yoon, Jin Young Ahn, Jung Ho Kim, Jun Yong Choi, Jong-Won Oh
Microbiology Resource Announcements Jan 2021, 10 (1) e01384-20; DOI: 10.1128/MRA.01384-20
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